The change that could affect it the most is the support for 32-bit apps being officially dropped. Whether you should upgrade your Macs to the new macOS Catalina is entirely up to your current workflow. Other notable changes include the abandonment of 32-bit apps in favour of 64-bit apps, refreshed Reminders, Photos, Mail, Safari, and Notes apps, and the introduction of Apple Arcade among others. It also officially kills the 20-year-old iTunes (on Mac) and brings separate apps to manage music and podcasts while also adding a new TV app. The update, named macOS Catalina, brings a bucket-full of new features including the ability of using iPad as an external screen for Mac.
Apple has just released the latest update to macOS.